Rezafungin Acetate

CAS No: 1396640-59-7

Purity: 95%

Molar Mass: 1285.44

Chemical Formula: C65H88N8O19

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Product Name: Rezafungin Acetate

CAS No: 1396640-59-7

Purity: 95%

Molar Mass: 1285.44

Chemical Formula: C65H88N8O19

Synonyms: Biafungin

Storage: Store at -20℃

Target: antifungal

Application: Rezafungin acetate (CAS: 1396640-59-7) is a novel echinocandin antifungal agent used in the treatment of invasive fungal infections, particularly those caused by Candida species. It functions by inhibiting the synthesis of β-(1,3)-D-glucan, an essential component of the fungal cell wall, leading to cell wall disruption and ultimately fungal cell death. Rezafungin exhibits broad-spectrum activity against Candida species, including fluconazole-resistant strains, as well as certain molds such as Aspergillus species. In pharmaceutical chemistry, rezafungin acetate’s unique chemical structure and mechanism of action represent significant advancements in antifungal therapy, offering a potent and well-tolerated treatment option for serious fungal infections. Its application underscores its importance in infectious disease management and improving outcomes for patients at risk of invasive fungal diseases, particularly those with compromised immune systems. Ongoing research aims to further elucidate rezafungin’s pharmacokinetics, efficacy, and safety profile, with the goal of expanding its clinical utility and addressing the growing challenge of antifungal resistance.

Reference:

Garcia-Effron, G. (2020). Rezafungin—mechanisms of action, susceptibility and resistance: similarities and differences with the other echinocandins. Journal of fungi, 6(4), 262.

Ham, Y. Y., Lewis, J. S., & Thompson III, G. R. (2021). Rezafungin: a novel antifungal for the treatment of invasive candidiasis. Future Microbiology, 16(1), 27-36.