Pramlintide

CAS No: 151126-32-8

Purity: 95%

Molar Mass: 3949.39

Chemical Formula: C171H267N51O53S2

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Product Name: Pramlintide

CAS No: 151126-32-8

Purity: 95%

Molar Mass: 3949.39

Chemical Formula: C171H267N51O53S2

Synonyms: Triproamylin, Amylin (human), 25-L-proline-28-L-proline-29-L-proline- (9CI), Pramlintide

Storage: Store at -20℃

Sequence: KCNTATCATQ RLANFLVHSS NNFGPILPPT NVGSNTY

Target: HT-29

Application: Pramlintide (CAS: 151126-32-8) is a notable pharmaceutical compound designed to complement insulin therapy in diabetes management. Functioning as an amylin analogue, pramlintide acts by mimicking the action of the endogenous hormone amylin, which is co-secreted with insulin. By slowing gastric emptying, suppressing glucagon release, and promoting satiety, pramlintide aids in postprandial glucose regulation. Its primary target is the amylin receptor, strategically addressing challenges in blood glucose control, especially during meals. Widely used in conjunction with insulin, pramlintide helps reduce post-meal glucose spikes and enhances overall glycemic control in individuals with type 1 and type 2 diabetes. The compound’s unique mechanism of action makes it a valuable addition to pharmaceutical strategies, offering a comprehensive approach to address various facets of diabetes pathology and improve patient outcomes.

Reference: Kommera, S. P., Kumar, A., Chitkara, D., & Mittal, A. (2024). Pramlintide an Adjunct to Insulin Therapy: Challenges and Recent progress in delivery. Journal of Pharmacology and Experimental Therapeutics, 388(1), 81-90.