Product Name: H3K27(Me2) (15-34)
Purity: 95%
Molar Mass: 2008.3
Chemical Formula: C86H154N30O25
Storage: Store at -20℃
Sequence: APRKQLATKAARKSAPATGG
Application: H3K27(Me2) (15-34) is a synthetic peptide corresponding to amino acids 15-34 of histone H3, dimethylated at the lysine 27 (K27) residue. This specific post-translational modification is critical in the regulation of gene expression by promoting the formation of repressive chromatin structures. Dimethylation of H3K27 is facilitated by the Polycomb Repressive Complex 2 (PRC2) and is integral to maintaining gene silencing during development and differentiation. It is also implicated in the progression of various cancers. The H3K27(Me2) (15-34) peptide serves as an essential tool in epigenetic research, aiding in the study of chromatin dynamics, gene regulation, and the exploration of targeted epigenetic therapies.
