Product Name: Dasiglucagon
CAS No: 1544300-84-6
Purity: 95%
Molar Mass: 3381.66
Chemical Formula: C152H222N38O50
Synonyms: ZP4207; ZP 4207; ZP-4207
Storage: Store at -20℃
Sequence: HSQGTFTSDYSKYLDXARAEEFVKWLEST
Target: glucagon receptors
Application: Dasiglucagon (CAS: 1544300-84-6) is a glucagon receptor agonist used in the treatment of severe hypoglycemia in patients with diabetes. It acts by binding to glucagon receptors in the liver, stimulating the release of glucose into the bloodstream through glycogenolysis and gluconeogenesis. Dasiglucagon is particularly effective in cases of severe hypoglycemia where traditional methods of glucose administration, such as oral intake or intravenous glucose, are not feasible. In pharmaceutical chemistry, dasiglucagon’s targeted action on glucagon receptors represents a significant advancement in the management of acute hypoglycemic episodes, providing a rapid and reliable means of restoring blood glucose levels to prevent neurological complications and other adverse effects associated with severe hypoglycemia. Its application underscores its importance in emergency medicine and diabetes care, offering a life-saving intervention for patients at risk of hypoglycemic emergencies. Additionally, ongoing research explores dasiglucagon’s potential in other therapeutic areas, such as glycemic control in diabetes management and the treatment of other metabolic disorders.
Reference:
Blair, H. A. (2021). Dasiglucagon: first approval. Drugs, 81(9), 1115-1120.
