Product Name: Trofinetide
CAS No: 853400-76-7
Purity: 95%
Molar Mass: 315.32
Chemical Formula: C13H21N3O6
Synonyms: NNZ-2566
Storage: Store at -20℃
Sequence: GXE
Application: Trofinetide (CAS: 853400-76-7) is a synthetic peptide drug currently under investigation for the treatment of Rett syndrome, a rare neurodevelopmental disorder primarily affecting females. It functions by modulating the activity of the neurotrophic factor insulin-like growth factor 1 (IGF-1) and the neuropeptide oxytocin, both of which play important roles in brain development and function. Trofinetide is believed to enhance synaptic connectivity, neuroplasticity, and neurotransmitter balance in the brain, potentially leading to improvements in cognitive, motor, and behavioral symptoms associated with Rett syndrome. In pharmaceutical chemistry, trofinetide’s targeted mechanisms of action represent a promising approach to addressing the underlying pathophysiology of Rett syndrome, offering hope for improved outcomes and quality of life for individuals affected by this devastating condition. Ongoing clinical trials aim to further evaluate trofinetide’s safety and efficacy, with the goal of ultimately providing a much-needed treatment option for Rett syndrome patients and their families.
Reference:
