Tertiapin-Q

CAS No: 910044-56-3

Purity: 95%

Molar Mass: 2452.0

Chemical Formula: C106H175N35O24S4

 

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Product Name: Tertiapin-Q

CAS No: 910044-56-3

Purity: 95%

Molar Mass: 2452.0

Chemical Formula: C106H175N35O24S4

Storage: Store at -20℃

Sequence: ALCNCNRIIIPHQCWKKCGKK

Application: Tertiapin-Q is a synthetic peptide derived from the venom of the honey bee Apis mellifera, specifically designed to inhibit certain potassium channels, including the inward-rectifier potassium channels (Kir1.1 and Kir3.x) and calcium-activated potassium channels (SK channels). By blocking these channels, Tertiapin-Q modulates cellular excitability and neurotransmitter release. This makes it a valuable tool for research in neurophysiology, cardiac function, and renal physiology. Its ability to precisely target specific ion channels offers potential therapeutic applications in treating conditions such as atrial fibrillation, epilepsy, and renal disorders, where potassium channel dysfunction is implicated.

Reference: Okada, M., Kozaki, I., & Honda, H. (2020). Antidepressive effect of an inward rectifier K+ channel blocker peptide, tertiapin-RQ. Plos one, 15(11), e0233815.