Product Name: Taltirelin
CAS No: 103300-74-9
Purity: 95%
Molar Mass: 405.41
Chemical Formula: C17H23N7O5
Synonyms: TA0910
Storage: Store at -20℃
Target: thyrotropin-releasing hormone receptor
Application: Taltirelin (CAS: 103300-74-9) is a synthetic thyrotropin-releasing hormone (TRH) analog used in the treatment of central hypothyroidism, a condition characterized by insufficient thyroid hormone production due to dysfunction of the hypothalamus or pituitary gland. It functions by binding to TRH receptors in the anterior pituitary gland, stimulating the release of thyroid-stimulating hormone (TSH), which in turn promotes the synthesis and secretion of thyroid hormones from the thyroid gland. Taltirelin helps to restore thyroid hormone levels and alleviate symptoms associated with hypothyroidism, such as fatigue, weight gain, and cold intolerance. In pharmaceutical chemistry, taltirelin’s structural similarity to TRH and selective activation of TRH receptors represent a targeted approach to managing central hypothyroidism, offering a specific and effective therapeutic option for patients with this condition. Its application underscores its importance in endocrinology and improving hormonal balance in individuals with central hypothyroidism. Additionally, ongoing research explores taltirelin’s potential in other endocrine disorders and its role in combination therapies, demonstrating its versatility in hormone replacement therapy.
Reference:
