Pam3CSK4 Biotin

Purity: 95%

Molar Mass: 1962.8

Chemical Formula: C103H192N14O17S2

 

* Please kindly note that our products are not to be used for therapeutic purposes and cannot be sold to patients.

Product Name: Pam3CSK4 Biotin

Purity: 95%

Molar Mass: 1962.8

Chemical Formula: C103H192N14O17S2

Storage: Store at -20℃

Sequence: Pam3C-SKKKK

Target: TLR1

Application: Pam3CSK4 Biotin is a synthetic lipopeptide that acts as a Toll-like receptor 2 (TLR2) agonist, conjugated with biotin for detection and affinity applications. By binding to TLR2, it activates the innate immune response, leading to the production of pro-inflammatory cytokines. This lipopeptide is widely used in immunology research to study TLR2 signaling pathways, innate immunity, and inflammatory responses. The biotinylation allows for easy detection, purification, and interaction studies using streptavidin-based systems. Pam3CSK4 Biotin is also utilized in vaccine development and adjuvant research to enhance immune responses.

Reference: Marre, M. L., Petnicki-Ocwieja, T., DeFrancesco, A. S., Darcy, C. T., & Hu, L. T. (2010). Human integrin α3β1 regulates TLR2 recognition of lipopeptides from endosomal compartments. PloS One, 5(9), e12871.