Neuropeptide FF

CAS No: 99566-27-5

Purity: 95%

Molar Mass: 1081.3

Chemical Formula: C54H76N14O10

 

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Product Name: Neuropeptide FF

CAS No: 99566-27-5

Purity: 95%

Molar Mass: 1081.3

Chemical Formula: C54H76N14O10

Storage: Store at -20℃

Sequence: FLFQPQRF

Target: NPFF1 and NPFF2

Application: Neuropeptide FF (NPFF) is a peptide neurotransmitter known for its role in modulating pain, opioid tolerance, and cardiovascular functions. It binds to NPFF1 and NPFF2 receptors, which are involved in the regulation of nociception, opioid receptor activity, and neuroendocrine responses. NPFF has been shown to counteract opioid-induced analgesia and develop tolerance, making it a significant focus of research in pain management and addiction studies. Additionally, NPFF influences blood pressure and heart rate, contributing to its potential therapeutic applications in cardiovascular diseases. Its multifaceted effects on pain, opioid modulation, and cardiovascular functions highlight NPFF’s importance in neurobiological and clinical research.

Reference: Nguyen, T., Marusich, J., Li, J. X., & Zhang, Y. (2020). Neuropeptide FF and its receptors: therapeutic applications and ligand development. Journal of medicinal chemistry, 63(21), 12387-12402.