Product Name: GsMTx4
CAS No: 1209500-46-8
Purity: 95%
Molar Mass: 4095.8
Chemical Formula: C185H273N49O45S6
Storage: Store at -20℃
Sequence: GCLEFWWKCNPNDDKCCRPKLKCSKLFKLCNFSF-NH2
Target: MSCs
Application: GsMTx4 (Grammostola spatulata Mechanosensitive Toxin 4) is a peptide toxin isolated from the tarantula Grammostola spatulata venom. It acts as a selective inhibitor of stretch-activated ion channels, particularly those involved in mechanotransduction processes in cells. By blocking these channels, GsMTx4 suppresses mechanical stress-induced responses, such as ion flux and cell signaling pathways. This peptide is widely used in biophysical and physiological research to study mechanosensitive channels, cell mechanics, and sensory transduction mechanisms. Its applications extend to exploring roles in cardiovascular physiology, neuronal mechanotransduction, and potential therapeutic strategies for conditions involving abnormal mechanosensitivity.
