Product Name: COG 133
CAS No: 514200-66-9
Purity: 95%
Molar Mass: 2169.7
Chemical Formula: C97H181N37O19
Storage: Store at -20℃
Sequence: LRVRLASHLRKLRKRLL
Target: α7 nicotinic acetylcholine
Application: COG 133 is a synthetic peptide derived from the apolipoprotein E (apoE) protein, known for its neuroprotective properties. It functions by mimicking the receptor-binding region of apoE, thereby inhibiting the interactions between apoE and its receptors on cell surfaces. This mechanism reduces oxidative stress and inflammation in the nervous system. COG 133 is primarily used in neurological research, including studies on Alzheimer’s disease, stroke, and other neurodegenerative conditions. Its applications extend to therapeutic development for brain injuries and neuroinflammatory diseases.
