Bombesin

CAS No: 31362-50-2

Purity: 95%

Molar Mass: 1619.9

Chemical Formula: C71H110N24O18S

 

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Product Name: Bombesin

CAS No: 31362-50-2

Purity: 95%

Molar Mass: 1619.9

Chemical Formula: C71H110N24O18S

Synonyms: Bombesin 14

Storage: Store at -20℃

Sequence: XQRLGNQWAVGHLM

Application: Bombesin is a peptide originally isolated from frog skin that acts as a potent agonist for the gastrin-releasing peptide (GRP) receptors. It stimulates the release of gastrin, cholecystokinin, and other gastrointestinal hormones, leading to increased digestive enzyme secretion and smooth muscle contraction. Bombesin’s role in regulating gastrointestinal motility and hormone release makes it a valuable tool in studying digestive processes and neuroendocrine signaling. Additionally, due to its expression in various cancers, Bombesin is being explored as a target for diagnostic imaging and therapeutic interventions in oncology, particularly in neuroendocrine and small cell lung cancers.

Reference: Ramos-Álvarez, I., Moreno, P., Mantey, S. A., Nakamura, T., Nuche-Berenguer, B., Moody, T. W., … & Jensen, R. T. (2015). Insights into bombesin receptors and ligands: highlighting recent advances. Peptides, 72, 128-144.