Antisauvagine-30

CAS No: 220673-95-0

Purity: 95%

Molar Mass: 3651.2

Chemical Formula: C161H273N47O47S

 

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Product Name: Antisauvagine-30

CAS No: 220673-95-0

Purity: 95%

Molar Mass: 3651.2

Chemical Formula: C161H273N47O47S

Synonyms: aSvg-30

Storage: Store at -20℃

Sequence: FHLLRKMXEXEKQEKEKQQAANNRLLLDXX

Application: Antisauvagine-30 is a synthetic peptide that functions as a selective antagonist of the corticotropin-releasing factor receptor 2 (CRFR2). By blocking this receptor, Antisauvagine-30 inhibits the effects of urocortins, which are involved in the stress response, cardiovascular regulation, and appetite control. This peptide is used in pharmaceutical research to explore the role of CRFR2 in stress-related disorders, such as anxiety and depression, as well as metabolic and cardiovascular diseases. Its specificity for CRFR2 makes it a valuable tool for dissecting the physiological and pathological functions of the CRF system.

Reference: Zorrilla, E. P., Roberts, A. J., Rivier, J. E., & Koob, G. F. (2013). Anxiolytic-like effects of antisauvagine-30 in mice are not mediated by CRF2 receptors. PLoS One, 8(8), e63942.