Adegramotide

CAS No: 1252802-98-4

Purity: 95%

Molar Mass: 1819.02

Chemical Formula: C87H123N19O24

 

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Product Name: Adegramotide

CAS No: 1252802-98-4

Purity: 95%

Molar Mass: 1819.02

Chemical Formula: C87H123N19O24

Synonyms: DSR-131617

Storage: Store at -20℃

Sequence: WAPVLDFAPPGASAYGSL

Application: Adegramotide (CAS: 1252802-98-4) is a novel peptide-based compound currently under investigation for its therapeutic potential in various medical conditions, particularly in the field of oncology. This peptide exhibits unique properties that make it a promising candidate for targeted therapy against specific molecular pathways involved in cancer progression and metastasis. Adegramotide is designed to interact with specific receptors or proteins present on cancer cells, thereby disrupting crucial signaling pathways that promote tumor growth and spread. By targeting these pathways, adegramotide aims to inhibit cancer cell proliferation, induce apoptosis (cell death), and potentially enhance the efficacy of existing cancer treatments such as chemotherapy and targeted therapy. In preclinical studies, adegramotide has demonstrated encouraging results in inhibiting tumor growth and metastasis in various cancer models, suggesting its potential as a therapeutic agent for cancer treatment. Clinical trials are currently underway to evaluate the safety, efficacy, and therapeutic potential of adegramotide in cancer patients, with the goal of providing new treatment options for individuals affected by this complex and challenging disease. If successful, adegramotide could represent a significant advancement in cancer therapy, offering a targeted approach to treating malignancies and improving patient outcomes.

Reference:

Spira, A., Hansen, A. R., Harb, W. A., Curtis, K. K., Koga-Yamakawa, E., Origuchi, M., … & Shaib, W. L. (2021). Multicenter, open-label, phase I study of DSP-7888 Dosing Emulsion in patients with advanced malignancies. Targeted Oncology, 16(4), 461-469.

Suginobe, N., Nakamura, M., Takanashi, Y., Ban, H., & Gotoh, M. (2023). Mechanism of action of DSP-7888 (adegramotide/nelatimotide) Emulsion, a peptide-based therapeutic cancer vaccine with the potential to turn up the heat on non-immunoreactive tumors. Clinical and Translational Oncology, 25(2), 396-407.