Ac2-12

Product Name: Ac2-12

CAS No: 256447-08-2

Purity: 95%

Molar Mass: 1351.6

Chemical Formula: C63H94N14O17S

Synonyms: GLXC-15094

Storage: Store at -20℃

Sequence: AMVSEFLKQAW

Application: Ac2-12 is a synthetic peptide derived from the annexin A1 protein, known for its anti-inflammatory properties. This peptide exerts its effects by binding to the formyl peptide receptor 2 (FPR2), modulating immune cell activity and reducing the production of pro-inflammatory cytokines. In pharmaceutical research, Ac2-12 is investigated for its potential to treat inflammatory diseases, such as rheumatoid arthritis and inflammatory bowel disease. Its specific action on FPR2 makes it a valuable tool for understanding immune responses and developing new anti-inflammatory therapies.

Reference: Lyngstadaas, A. V., Olsen, M. V., Bair, J., Yang, M., Hodges, R. R., Utheim, T. P., … & Dartt, D. A. (2023). Anti-inflammatory and pro-resolving actions of the N-Terminal peptides Ac2-26, Ac2-12, and Ac9-25 of Annexin A1 on Conjunctival Goblet cell function. The American Journal of Pathology, 193(11), 1817-1832.