Product Name: H3K27(Me3) (15-34)
Purity: 95%
Molar Mass: 2023.4
Chemical Formula: C87H157N30O25
Storage: Store at -20℃
Sequence: APRKQLATKAARKSAPATGG
Application: H3K27(Me3) (15-34) is a synthetic peptide corresponding to amino acids 15-34 of histone H3, trimethylated at the lysine 27 (K27) residue. This post-translational modification is a key epigenetic mark associated with transcriptional repression and the formation of heterochromatin. The trimethylation of H3K27 is mediated by the Polycomb Repressive Complex 2 (PRC2) and plays a vital role in gene silencing, developmental processes, and the maintenance of stem cell identity. H3K27(Me3) (15-34) is widely utilized in epigenetic research to study chromatin dynamics, gene regulation, and the mechanisms underlying various diseases, including cancer. Its application is crucial for developing targeted epigenetic therapies.
