Product Name: Apraglutide
CAS No: 1295353-98-8
Purity: 95%
Molar Mass: 3765.25
Chemical Formula: C172H263N43O52
Synonyms: FE 203799
Storage: Store at -20℃
Sequence: HGDGSFSDE-{Nle}-{d-Phe}-TILDLLAARDFINWLIQTKITD-NH2
Application: Apraglutide (CAS: 1295353-98-8) is a synthetic peptide analog of glucagon-like peptide-2 (GLP-2), a hormone involved in the regulation of gastrointestinal function and nutrient absorption. Apraglutide acts as a GLP-2 receptor agonist, stimulating intestinal growth and improving nutrient absorption in the small intestine. It has shown potential therapeutic applications in the treatment of gastrointestinal disorders characterized by intestinal failure, such as short bowel syndrome (SBS). By promoting intestinal growth and function, apraglutide may help reduce dependence on parenteral nutrition and improve overall nutritional status in patients with SBS. Clinical trials have demonstrated the efficacy and safety of apraglutide in increasing intestinal absorption, reducing diarrhea, and improving quality of life in patients with SBS. However, further research is needed to optimize dosing regimens, evaluate long-term safety, and explore additional therapeutic indications for apraglutide.