Product Name: Daridorexant
CAS No: 1505484-82-1
Purity: 95%
Molar Mass: 450.93
Chemical Formula: C23H23ClN6O2
Synonyms: Nemorexant, ACT541468
Storage: Store at -20℃
Target: orexin receptor
Application: Daridorexant (CAS: 1505484-82-1) is a dual orexin receptor antagonist (DORA) used in the treatment of insomnia. It functions by selectively blocking the activity of orexin receptors in the brain, specifically targeting both orexin receptor 1 (OX1R) and orexin receptor 2 (OX2R). Orexin, also known as hypocretin, is a neuropeptide involved in regulating wakefulness and arousal. By inhibiting orexin signaling, daridorexant promotes sleep initiation and maintenance without causing significant sedation or next-day residual effects commonly associated with traditional sedative-hypnotic medications. In pharmaceutical chemistry, daridorexant’s targeted action on orexin receptors represents a novel approach to treating insomnia, offering a more specific and potentially safer alternative to conventional sleep aids. Its application underscores its importance in improving sleep quality and overall well-being for individuals with insomnia. Additionally, ongoing research explores daridorexant’s potential in other sleep-related disorders and its role in combination therapies, demonstrating its versatility in sleep medicine and neuropharmacology.
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