Carbetocin

CAS No: 37025-55-1

Purity: 95%

Molar Mass: 988.16

Chemical Formula: C45H69N11O12S

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Product Name: Carbetocin

CAS No: 37025-55-1

Purity: 95%

Molar Mass: 988.16

Chemical Formula: C45H69N11O12S

Synonyms: Depotocin, LV 101, Pabal

Storage: Store at -20℃

Sequence: XYIQNCPLG

Target: oxytocin receptor

Application: Carbetocin (CAS: 37025-55-1) is a synthetic analog of oxytocin, a hormone involved in uterine contractions during labor and milk ejection during breastfeeding. It acts as a long-acting oxytocin agonist, binding to oxytocin receptors on uterine smooth muscle cells to stimulate contractions. Carbetocin is primarily used to prevent postpartum hemorrhage (excessive bleeding after childbirth) by promoting uterine contraction and tone after delivery. This helps to reduce the risk of uterine atony, a major cause of postpartum hemorrhage. In pharmaceutical chemistry, carbetocin’s extended duration of action and efficacy in preventing postpartum hemorrhage make it a valuable addition to obstetric care, improving maternal outcomes and reducing the need for interventions such as manual removal of the placenta or surgical procedures. Its application highlights its significance in addressing critical maternal health concerns globally, particularly in settings with limited access to emergency obstetric care. Additionally, ongoing research explores carbetocin’s potential in other obstetric and gynecological indications, further expanding its therapeutic utility in women’s health.

Reference:

Peters, N. C., & Duvekot, J. J. (2009). Carbetocin for the prevention of postpartum hemorrhage: a systematic review. Obstetrical & gynecological survey, 64(2), 129-135.

Costa, B. Y., Santos, L. G., Marianno, P., Rae, M., de Almeida, M. G., de Brito, M. C., … & Camarini, R. (2023). Carbetocin Inhibits Behavioral Sensitization to Ethanol in Male and Female Mice, Independent of Corticosterone Levels. Toxics, 11(11), 893.