Product Name: Atosiban
CAS No: 90779-69-4
Purity: 95%
Molar Mass: 994.19
Chemical Formula: C43H67N11O12S2
Synonyms: Antocin II, CAP 449, ORF 22164
Storage: Store at -20℃
Sequence: XYITNCPXG
Target: vasopressin/oxytocin receptor
Application: Atosiban (CAS: 90779-69-4) is a synthetic peptide drug used as an oxytocin receptor antagonist. It exerts its pharmacological effects by competitively blocking the binding of oxytocin to its receptors on the smooth muscle cells of the uterus. This inhibition leads to the suppression of uterine contractions, making atosiban valuable in the management of preterm labor. By delaying labor, atosiban helps to prolong pregnancy and improve neonatal outcomes. In pharmaceutical chemistry, the development of atosiban represents a significant advancement in obstetric medicine, providing a targeted approach to prevent preterm birth and reduce associated complications. Its application in preterm labor management underscores its importance in improving maternal and fetal health outcomes. Additionally, ongoing research explores atosiban’s potential in other conditions characterized by uterine hyperactivity, such as dysmenorrhea and uterine fibroids, highlighting its versatility in women’s health therapeutics.
Reference: Tsatsaris, V., Carbonne, B., & Cabrol, D. (2004). Atosiban for preterm labour. Drugs, 64, 375-382.