Product Name: Mifamurtide
CAS No: 83461-56-7
Purity: 95%
Molar Mass: 1237.5
Chemical Formula: C59H109N6O19P
Synonyms: CGP 19835, L-MTP-PE, MLV 19835
Storage: Store at -20℃
Target: NOD2
Application: Mifamurtide (CAS: 83461-56-7), also known as muramyl dipeptide-phosphatidylethanolamine, is a synthetic immunostimulant drug used in the treatment of osteosarcoma, a type of bone cancer. It functions by activating monocytes and macrophages via interaction with toll-like receptor 2 (TLR2), leading to the release of cytokines such as interleukin-1 (IL-1) and tumor necrosis factor-alpha (TNF-α). This immune activation enhances the body’s antitumor response and helps in the elimination of cancer cells. Mifamurtide is typically administered as adjuvant therapy following surgical resection of osteosarcoma to reduce the risk of disease recurrence. In pharmaceutical chemistry, the development of mifamurtide represents a milestone in the field of cancer immunotherapy, providing a targeted approach to bolster the immune system’s ability to recognize and destroy malignant cells. Its application in osteosarcoma treatment underscores its significance in improving outcomes for patients with this aggressive form of cancer. Additionally, ongoing research explores mifamurtide’s potential in combination therapies and its efficacy in other malignancies, reflecting its importance in advancing cancer treatment strategies.
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