Product Name: Vosoritide
CAS No: 1480724-61-5
Purity: 95%
Molar Mass: 4102.73
Chemical Formula: C176H290N56O51S3
Synonyms: BMN 111
Storage: Store at -20℃
Sequence: PGQEHPNARK YKGANKKGLS KGCFGLKLDR IGSMSGLGC
Target: NPR-B
Application: Vosoritide (CAS: 1480724-61-5) is a pharmaceutical agent designed to address skeletal growth disorders, specifically achondroplasia. As a C-type natriuretic peptide (CNP) analog, vosoritide acts by activating the CNP receptor, playing a crucial role in regulating bone growth. Its mechanism involves promoting chondrocyte proliferation and inhibiting hypertrophy in the growth plates of bones, ultimately contributing to increased longitudinal bone growth. Vosoritide’s targeted approach addresses the underlying molecular pathway associated with achondroplasia, the most common form of dwarfism. This makes vosoritide a groundbreaking intervention in the pharmaceutical landscape, offering a specific and promising solution to enhance growth in individuals affected by this skeletal disorder.
Reference: Duggan, S. (2021). Vosoritide: first approval. Drugs, 81(17), 2057-2062.
