Product Name: Icatibant
CAS No: 130308-48-4
Purity: 95%
Molar Mass: 1304.52
Chemical Formula: C59H89N19O13S
Synonyms: D-Arginyl-L-arginyl-L-prolyl-(4R)-4-hydroxy-L-prolylglycyl-3-(2-thienyl)-L-alanyl-L-seryl-(3R)-1,2,3,4-tetrahydro-3-isoquinolinecarbonyl-(2S,3aS,7aS)-octahydro-1H-indole-2-carbonyl-L-arginine (ACI)
Storage: Store at -20℃
Sequence: RRPXGXSXXR
Target: bradykinin B2 receptor
Application: Icatibant (CAS: 130308-48-4) is a pharmaceutical agent with significance in the field of hereditary angioedema (HAE) management. As a selective bradykinin B2 receptor antagonist, icatibant plays a pivotal role in controlling the symptoms of acute attacks associated with HAE. By blocking the binding of bradykinin to its receptors, icatibant effectively inhibits vasodilation and vascular permeability, which are hallmarks of HAE episodes. The targeted action of icatibant provides rapid relief from symptoms such as swelling and pain. This makes icatibant a crucial tool in the pharmaceutical armamentarium for managing HAE, offering patients a specific and effective intervention to alleviate the impact of this genetic disorder.
