Degarelix

CAS No: 214766-78-6

Purity: 95%

Molar Mass: 1632.26

Chemical Formula: C82H103ClN18O16

 

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Product Name: Degarelix

CAS No: 214766-78-6

Purity: 95%

Molar Mass: 1632.26

Chemical Formula: C82H103ClN18O16

Synonyms: Firmagon

Storage: Store at -20℃

Sequence: XFASFFLKPA

Target: GnRHR

Application: Degarelix (CAS: 214766-78-6) is a potent pharmaceutical agent designed for the management of advanced prostate cancer. Functioning as a gonadotropin-releasing hormone (GnRH) receptor antagonist, degarelix effectively suppresses the production of testosterone, a hormone that fuels the growth of prostate cancer cells. By rapidly and profoundly reducing serum testosterone levels, degarelix provides a swift and sustained hormonal blockade, offering a valuable alternative to traditional GnRH agonists. This targeted suppression of testosterone production helps alleviate symptoms and slow the progression of prostate cancer. Degarelix’s mechanism of action makes it particularly beneficial in situations where a rapid reduction in testosterone is crucial, highlighting its significance in the pharmaceutical landscape for the treatment of advanced prostate cancer.

Reference: Zengerling, F., Jakob, J. J., Schmidt, S., Meerpohl, J. J., Blümle, A., Schmucker, C., … & Kunath, F. (2021). Degarelix for treating advanced hormone‐sensitive prostate cancer. The Cochrane Database of Systematic Reviews, 2021(8).