Product Name: Teduglutide
CAS No: 197922-42-2
Purity: 95%
Molar Mass: 3752.13
Chemical Formula: C164H252N44O55S
Synonyms: ALX 0600, Revestive, Gattex
Storage: Store at -20℃
Sequence: HGDGSFSDEM NTILDNLAAR DFINWLIQTK ITD
Target: GLP-2
Application: Teduglutide (CAS: 197922-42-2) represents a significant advancement in pharmaceuticals, particularly in the field of gastrointestinal disorders. As a glucagon-like peptide-2 (GLP-2) analogue, teduglutide plays a crucial role in intestinal function and nutrient absorption. Its mechanism involves stimulating intestinal growth and enhancing nutrient absorption by promoting crypt cell proliferation and reducing apoptosis. Teduglutide is primarily employed for the treatment of short bowel syndrome (SBS), a condition characterized by significant intestinal resection leading to malabsorption. By addressing the underlying intestinal insufficiency, teduglutide contributes to the restoration of intestinal function and nutrient absorption, reducing dependence on parenteral nutrition. This targeted approach makes teduglutide a valuable pharmaceutical tool in improving the quality of life for individuals with SBS, exemplifying its role in addressing specific gastrointestinal challenges.
Reference: Irles-Rocamora, J. A. (2023). Review of real-life teduglutide experience. Nutricion Hospitalaria.